Estrogen and testosterone are very similar in composition and can both effect target tissue similarly.  In fact, estrogen is produced from testosterone. Within the ovaries a reaction occurs in which the testosterone (with 19 carbon atoms) interacts with an enzyme that acts to remove a single carbon atom from the compound, producing estrogen (with 18 carbon atoms).

We have also described the absolute importance of estrogen on genital tissues to prevent genital atrophy. Both systemic estrogen (oral pills, transdermal patches, transdermal creams) and topical vaginal creams can supply adequate replacement estrogen to the genital tissues if needed. However, for these you need the assistance of your gynecologist.

Estrogen is also necessary for the adequate clitoral blood flow needed to establish sexual arousal and a clitoral erection. Since an orgasm can only be achieved from the continued stimulation of a completely erect clitoris, estrogen is necessary for optimal sexual arousal of the clitoris. Further, estrogen is also necessary for the lubrication of the vagina, which is a significant component of a woman’s sexual arousal.

Estrogen is important to establish a maximum clitoral erection not only by improving blood flow, but also by optimizing the nitric oxide synthase (NOS) pathway to dilate the corpus cavernosa . The all important NOS pathway that establishes a clitoral erection is dependant upon both estrogen and testosterone. Testosterone is probably more important than the estrogen, but remember they are both very similar and related to one another. In fact, in every clinical study to test the ability of testosterone to increase a woman’s sexual desire and sexual arousal, researchers first make sure the participants are on estrogen replacement therapy. This is done so that they can study the effects of the testosterone medication with the assurance that every participant had similar estrogen levels. Remember, every woman is unique and complex!

As already mentioned, men usually achieve orgasm long before a woman does. This is due to the fact that women are complex!

The ability for a woman to achieve an orgasm depends on:
•    Adequate estrogen hormone levels
•    Adequate testosterone hormone levels
•    Sufficient sexual arousal to establish a full clitoral erection
•    Adequate stimulation of a completely aroused and erect clitoris for a sufficient period to elicit orgasm

L-arginine comes primarily from dietary intake, and is the only starting point for the Nitric Oxide Synthase pathway. When the electrical signal of sexual arousal activates the NOS pathway, L-arginine becomes converted into nitric oxide. Nitric oxide acts as a vasodilator and promotes yet another more powerful element,  cyclic-GMP, a very potent vasodilator.

What results is a build-up of this potent vasodilator thus creating a penile erection. Though the producer of this drug (Pfizer Pharmaceuticals) has tried to prove this drug effective for women, there have been little positive results. The reason that sildenafil cannot be proven to be beneficial for women is probably due to the fact that the NOS pathway is very sensitive to, and in need of adequate testosterone and estrogen. Remember, women are complex!

While the Nobel Prize in Medicine was not awarded for the knowledge that to have an orgasm it is essential to become maximally sexually aroused with a clitoral erection, the discovery of the science underlying genital erection did. The physiology that enables a woman to establish a clitoral erection (and a man a penile erection) is the Nitric Oxide Synthase Pathway.  The discovery of this pathway was the basis of the 1998 Nobel Prize in Medicine.   Now we know that the NOS pathway explains how a signal originating in the brain and traveling via the nerves (esp. the clitoral nerve) causes the release of nitric oxide, the key event that results in clitoral engorgement and clitoral erection.

This NOS pathway relies on the presence of L-arginine, a semi-essential amino acid that is usually contained in most cells of the body (esp. blood vessels). It is this amino acid that causes the dilation of blood vessels, an important step resulting in vaso-congestion and thus an erection.  While it is not L-arginine itself that acts directly on the tissue, L-arginine and only L-arginine makes this possible by its conversion into other compounds.

This induced production of two important vasodilators is like throwing gasoline onto a smoldering fire, causing a large and rapid reaction. This NOS  mechanism creates maximum sexual arousal and clitoral erection by inducing the activity of nitric oxide with L-arginine.

The fact is our brain is the main sexual organ and its where all the magic of sex and intimacy begins.  The nerves in the brain and spinal cord causes a chain reaction, leading to direct stimulation of the pelvic nerves that lead to the vagina and clitoris.

The initial stimulation of the pelvic nerves causes an enlargement of the blood vessels that supply the vagina and clitoris. Genital stimulation creates the sensation of pleasure in the brain, which then acts to increase electrical action of the pelvic nerves to increase vaginal and clitoral blood vessel changes.

A woman’s sexual arousal is not like the ON/OFF switch of a light, but rather like a car rolling down a steep hill. Just like how a car rolling down a hill builds up speed with time, a woman’s sexual arousal builds in intensity over a period of time.

The progressive and increasing stimulation of the pelvic nerves causes these very specialized nerves to release small pockets of vaso-active intestinal polypeptides (VIP – first described from the intestines). These cause the blood vessels that surround the vagina to dilate (causing more blood flow).

Both the small arteries (arterioles), that supply fresh blood to the tissue as well as the small veins (venules), that drain blood from the tissue become dilated. What results is an increased amount of blood arriving at the tissue, while at the same time even less blood being allowed to drain away. The net effect that occurs is a tissue engorged or saturated with blood. This is called vaso-congestion, and it is the basis of all sexual arousal both in the vagina and in the clitoris.

With vaso-congestion the vessels that surround the vagina become permeable (porous) and allow the fluid component of blood to saturate the vaginal mucosa in-between the cells.  This fluid component of blood accumulates in the lumen of the vagina and provides the vaginal lubrication.  Vaginal lubrication is the initial vaso-congestive response of a woman’s sexual arousal.

Tomorrow’s entry will be a bit more fun, but it is alway good to have a little class time!

Cheers,

Cyn

Sensua Customer Care – also an avid user

The term “clitoral erection” cannot be found in the medical literature before the 1990’s.  The knowledge and understanding that a woman’s clitoris must become fully erect so we can have orgasm is the basis of the Second Sexual Revolution for Women. 

As with men, they cannot achieve orgasm without a penile erection;   This knowledge is becoming well known to women; but few men understand how a woman achieves orgasm, and the importance of an orgasm to women.  Once again, sexual satisfaction is defined and achieved only by an orgasm.

So what it Key to the Kingdom -Vaso-congestion is the key!Vaso-congestion is the medical term that describes the action where more blood is going in to an organ than is released. Just as in the male penis, the female clitoris has an internal structure termed the ‘corpus cavernosa.’ (In Latin: Corpus=Body, Cavernosa=Caves.)

Think of it as a sponge.  In a non aroused state, the sponge is dry; in the sexually aroused state the sponge fills with blood and grows to several times its original size.  This vaso-congestion causes the clitoris to increase in length and diameter and protrudes erectly outside of the clitoral hood.

This is a cold “hard”  fact(no pun intended) as it  allows for a higher degree of physical stimulation during sexual activity.  The most important result of an erect clitoris is that the sexual sensory nerves become hypersensitive to touch -  ladies you know what I am refering to!   This hypersensitivity of the clitoral nerves allows a women to achieve orgasm.

More cool info from the Sensua Team later this week.

Cheers,

Cyn

Cynthia, Sensua! Customer Care team

• Hypoactive Sexual Desire Disorder
• Hypoactive Sexual Arousal Disorder
• Orgasmic Disorder or Anorgasmia  –  “An” or “A” before a word means without.   Anorgasmia is defined as the lack of an orgasm.

For those of us who have to work at it, sexual satisfaction is actually having orgasm. The only way to have one is to have enough interest, sexual desire, and sexual arousal.  These are the trifecta for toe-curling, mind-melding orgasms.  When one of these are missing, we begin to think something is wrong.

To diagnose sexual dysfunction, the FDA requires that the reported lack of desire, lack of sexual arousal, or lack of an orgasm causes distress for an individual woman.  The FDA needs a medical diagnosis to be able to evaluate the effectiveness of a specific drug (when compared to placebo) in treating the symptoms which cause the dysfunction or disorder.  Speaking from experience, “distress” – reads as frustration & despair.

So, in 2001, the FDA issued clinical study guidelines for the evaluation of drugs meant to treat Female Sexual Dysfunction.  Since then we have seen many oils, rubs, herbal remedies, but no drugs have yet to gain FDA-approval for the treatment of Female Sexual Dysfunction!

Thankfully, there is Sensua! which was developed by real Ob-Gyn board-certified doctors and cleared by the FDA, safe and effective.  Sister, if you are on the fence about it, try the Intro Kit, follow the directions to apply and you will have a awesome experience!  If not, Sensua! has a 60-day money back guarantee.

Cheers,

Cyn

Sensua Customer Care

Women are complex! Several inter-connected factors impact our ability to achieve sexual satisfaction, including estrogen, testosterone, and progesterone levels.  These hormone levels are affected by age, oral contraceptives, and some antidepressant medications, and can heavily influence a woman’s normal sexual response. (Sexual Desire, Sexual Arousal including vaginal lubrication and clitoral erection, Orgasm!)

To be able to market a medication like Viagra¨ to women, clinical studies must be done that prove, to the FDA (Food and Drug Administration) and the medical community, that the medication is safe and effective.  Effectiveness is always measured against a placebo (sugar pill).   For women, Viagra could not prove any effectiveness over placebo in several large clinical studies, which were commissioned and paid for by Pfizer, the pharmaceutical company that produces Viagra.  One study did however show that Viagra¨ can improve a woman’s sexual responses; but only if her estrogen, testosterone, and progesterone levels were optimized using hormone replacement therapy along with the medication.  Further, it was only effective when hormone levels were equivalent to that of a 20 year old woman in the prime of her Sexual Health – not much help for us older women.

In the meantime, take advantage of our 15% off promotional program and try Sensua! today. You will be glad you did!

In 1957 the first oral contraceptives for women were FDA-approved for use.  The pill really didn’t gain public acceptance until the mid-1960’s.  This was the first time  hormone-based oral contraceptives allowed women to take control of their reproduction, thus freeing women from the fear of becoming pregnant.

The 2nd Sexual Revolution

Our 2nd sexual revolution began in 1998 with the introduction, sale, and general acceptance of Viagra (Pfizer Pharmaceuticals).  Viagra was the first oral therapy for male impotence, and was marketed aggressively by Pfizer as a solution to “ED” or “erectile dysfunction”.  This drug addressed the simple fact that men cannot engage in sexual intercourse without a penile erection.  With this problem solved, men now experience orgasm over 95% of the time when sexually active.   How do we women achieve that same level of pleasure as men?

The 3rd Sexual Revolution

The 3rd sexual revolution for women is the new understanding that we should also achieve orgasm over 95% of the time we engage in sex.  Women should expect sexual satisfaction; the ability to expect to achieve orgasm every time that they are sexually active.  Sensua! guarantees a whole new level of intensity in your physical sexual experience.  It really can take your intimacy to a new intensity.

Let’s break down our orgasmic experience:
1.  Sexual Desire (or Libido):  desire for a satisfying sexual experience.  This is our mind at work getting in the mood.

2.  Sexual Arousal:  vaginal lubrication and clitoral erection.  Sensua!’s patented formulation ensures maximum clitoral fullness and enlargement thereby maximizing orgasmic intensity.

3.  Orgasm:  A woman can only achieve orgasm from either; stimulation of the completely erect clitoris, or the G-spot, which is just inside the top of the vagina and supplied with a network of nerves from the clitoris.

So if your mind is in the right place, Step 1 is already done.  Often, as we get older and with busy daily routines, we need help with Step 2.  Try Sensua! today, to make sure you get to Step 3 and then some!

Cheers,

Cyn

But then there is Sensua! arousal gel. It is FDA cleared safe and effective for the enhanced sensitivity and intensity of your next sexual encounter. The Sensua! product is backed by years of clinical study, which won FDA clearance and continues to receive thanks and appreciation from satisfied women of all ages daily.

It is not just about the slip-slide factor, which is where the other products focus.  The special compounds in Sensua! fill the clitoris with blood enhancing clitoral erection. Clearly when the clitoris is fully involved we get those mind-blowing-toe-curling orgasms that we all want everyday!

For the ultimate compliment and to take sexy to a whole new level in your life, we recommend taking advantage of our daily therapy programs. If you don’t at least try the Intro Kit, you will never know what you are missing.  Afterall, a sexually gratified woman is a totally different creature.

Be sure to check the blog and our testimony page often to see other satisfied women share in their Sensua! experience.